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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG2
All Species:
11.82
Human Site:
S420
Identified Species:
20
UniProt:
Q9UNQ0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNQ0
NP_004818.2
655
72314
S420
Y
F
G
L
K
N
D
S
T
G
I
Q
N
R
A
Chimpanzee
Pan troglodytes
XP_526633
860
94544
S625
Y
F
G
L
K
N
D
S
T
G
I
Q
N
R
A
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
T420
F
G
L
N
N
D
S
T
G
I
Q
N
R
A
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMS5
657
72959
D419
I
Y
F
D
L
K
Y
D
A
A
G
M
Q
N
R
Rat
Rattus norvegicus
Q80W57
657
72942
D419
L
Y
F
G
L
K
N
D
P
T
G
M
Q
N
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510302
654
72378
N417
I
F
F
G
L
E
D
N
Q
T
G
I
Q
N
R
Chicken
Gallus gallus
XP_421638
651
72109
D422
I
F
F
G
V
K
L
D
E
S
G
I
Q
N
R
Frog
Xenopus laevis
NP_001091141
661
73548
E418
A
I
F
F
G
V
K
E
D
V
S
G
I
Q
N
Zebra Danio
Brachydanio rerio
NP_001036240
643
71395
S413
F
F
G
V
A
E
N
S
S
G
I
Q
N
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
Q456
F
L
G
Q
Q
L
T
Q
V
G
V
M
N
I
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
R377
G
I
M
F
N
H
I
R
N
M
N
F
M
L
Q
Sea Urchin
Strong. purpuratus
XP_789781
628
69714
T407
P
S
G
T
Q
N
R
T
G
A
F
L
F
A
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93YS4
751
82913
T443
N
S
G
R
E
T
Q
T
G
K
P
S
P
A
A
Baker's Yeast
Sacchar. cerevisiae
P25371
1049
117213
P765
N
V
L
N
G
D
L
P
T
G
Q
Q
S
A
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.4
96.6
N.A.
N.A.
81.8
81.4
N.A.
75.8
62.4
68.2
60.9
N.A.
31.5
N.A.
29.6
45
Protein Similarity:
100
75.9
97.7
N.A.
N.A.
89.6
89.1
N.A.
88.2
78.3
82.1
77.8
N.A.
51.6
N.A.
48.4
63.8
P-Site Identity:
100
100
0
N.A.
N.A.
0
0
N.A.
13.3
6.6
0
53.3
N.A.
20
N.A.
0
13.3
P-Site Similarity:
100
100
20
N.A.
N.A.
6.6
13.3
N.A.
20
6.6
6.6
80
N.A.
40
N.A.
6.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
0
0
0
8
15
0
0
0
29
22
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
15
22
22
8
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
8
15
0
8
8
0
0
0
0
0
0
% E
% Phe:
22
36
36
15
0
0
0
0
0
0
8
8
8
0
0
% F
% Gly:
8
8
43
22
15
0
0
0
22
36
29
8
0
0
15
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
22
15
0
0
0
0
8
0
0
8
22
15
8
8
0
% I
% Lys:
0
0
0
0
15
22
8
0
0
8
0
0
0
0
0
% K
% Leu:
8
8
15
15
22
8
15
0
0
0
0
8
0
8
0
% L
% Met:
0
0
8
0
0
0
0
0
0
8
0
22
8
0
8
% M
% Asn:
15
0
0
15
15
22
15
8
8
0
8
8
29
29
15
% N
% Pro:
8
0
0
0
0
0
0
8
8
0
8
0
8
0
0
% P
% Gln:
0
0
0
8
15
0
8
8
8
0
15
29
29
8
8
% Q
% Arg:
0
0
0
8
0
0
8
8
0
0
0
0
8
22
29
% R
% Ser:
0
15
0
0
0
0
8
22
8
8
8
8
8
0
8
% S
% Thr:
0
0
0
8
0
8
8
22
22
15
0
0
0
0
0
% T
% Val:
0
8
0
8
8
8
0
0
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
15
15
0
0
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _